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Check rooms and rates
From114US$ /night
Check-in
11Jan2026Select date
Check-out
12Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

Piazza Dell'Unita 24, Rome, Italy, 00192
-
Close to the Vatican Museums
Perfect
9.4
/10
5.0
/5

Rooms with City Views

Domus Serafino offers double rooms with private bathrooms, flat-screen TVs, and soundproof walls. Each room includes air conditioning, a tea/coffee maker, and an electric kettle. Rooms feature tile or marble floors and provide city views.

Breakfast at Nearby Café

Breakfast is served at a café located near the property. Guests have access to a shared kitchen for additional food preparation needs.

Free WiFi Throughout

The property provides free WiFi access in all areas. Ironing facilities and heating are available for guest use.

Vatican and Shopping Access

Domus Serafino is on Via Cola di Rienzo, one of Rome's largest shopping streets. The Vatican is 700 meters away. The Colosseum is 3 km, Piazza Navona is 1.5 km, and Castel Sant'Angelo is 1 km from the property.

Practical Guest Services

The property offers free toiletries and hairdryers in each room. Children under 12 years stay free. Rome Fiumicino Airport is 16 km from Domus Serafino.

“Domus Serafino impresses with its prime location on Via Cola di Rienzo, a shopper's paradise, and its easy access to the Vatican. I think it's a smart choice, blending the charm of a residential neighborhood with the convenience of nearby shops and restaurants. The soundproofed rooms and thoughtful amenities, like the shared kitchen, really stood out to me as guest-focused.”
Hotel logo
Grace WhitmanContent & Editorial Director at Familyhotels
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Choose from a variety of room types

Choose from a wide variety of rooms designed for families, including double rooms, family suites, and rooms with breakfast included
Double Room
2 persons
14 m² 
1 King-size bed
Shower
Coffee machine
Standard Double Room
2 persons
14 m² 
1 King-size bed
Shower
Coffee machine
Deluxe Double Room
2 persons
17 m² 
1 King-size bed
Shower
Coffee machine

Availability and pricing for your selected dates

Book your family’s getaway in a snap with up-to-date availability and pricing!

Facilities

Each family-friendly hotel provides top-notch amenities for an unforgettable stay with your loved ones

General

  • No smoking on site
  • Free Wi-Fi
  • Safe deposit box
  • No pets allowed
  • Lift
  • Fire extinguishers
  • Key access

Guest Parking

  • Electric kettle

Children

  • Cots

Room features

  • Air conditioning
  • Heating
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Electric kettle

Media

  • Flat-screen TV

Room decor

  • Parquet floor
Show more

Location

Piazza Dell'Unita 24, Rome, Italy, 00192
Map view
Piazza Dell'Unita 24, Rome, Italy, 00192
Nearby
Square
Piazza del Risorgimento
460 m
Restaurants
Ai Balestrari in Prati
70 m
P.zza dell'Unita
Enoteca Vini Vizi e Virtu
10 m
Piazza Dell'Unita' 15
Alla Rampa dei Gracchi
40 m
Via Dei Gracchi 86 - 92
Il Matriciano
120 m
55 Via dei Gracchi
La Zanzara
280 m
84 Via Crescenzio
Cantiani
80 m
Via Cola Di Rienzo
Caffetteria dei Gracchi
80 m
Via Fabio Massimo 27
Guttilla Alta Gelateria Italiana
70 m
Via Dei Gracchi 93/95 Angolo via Fabio Massimo
Gerbillo Furioso
140 m
Via Germanico 103 Metro Ottaviano
Franchi Gastronomia
170 m
Via Cola di Rienzo 200
Explore Rome
Explore Rome
Top Attractions
Activities
Dining
Entertainment
Vatican Museums
12 minutes walking
Home to stunning art collections, including the Sistine Chapel. Reservations recommended. Access on select free admission days.
St. Peter's Basilica
15 minutes walking
A magnificent church, featuring breathtaking architecture and art. Climb the dome for a panoramic view of Rome.
Piazza Navona
20 minutes walking
A vibrant square filled with Baroque architecture, fountains, and outdoor cafes, perfect for soaking in the local culture.
Colosseum
12 minutes driving
An iconic symbol of Rome, this ancient amphitheater offers guided tours detailing its history and architecture.
Biking along the Tiber River
15 minutes walking
Enjoy scenic views on a bike ride. Rentals available nearby; perfect for mixing exercise with exploration.
Yoga in the Vatican Gardens
12 minutes walking
Relax with yoga classes amidst beautiful greenery. Check seasonal schedules for sessions tailored to all levels.
Vespa Tours
10 minutes driving
Experience exhilarating rides through Rome's streets. Guided Vespa tours available for thrill-seekers wanting adventure.
Enoteca Vini Vizi e Virtu
1 minute walking
Charming wine bar offering local dishes and an extensive wine selection. Reservations suggested for peak times.
Ai Balestrari in Prati
1 minute walking
Cozy trattoria known for authentic Roman cuisine. Signature dishes include carbonara and tiramisu.
La Zanzara
4 minutes walking
Modern bistro with a lively atmosphere. A great spot for brunch, offering vegetarian options and creative cocktails.
Teatro dell'Opera di Roma
12 minutes driving
Renowned venue for operas and ballets. Experience world-class performances in a historic setting.
Trastevere Nightlife
18 minutes driving
Vibrant area filled with bars and live music. Perfect for an evening out, offering both local and international flavors.
Tips on navigating the city
City Centre
Rome35 min  ·  2.9 km
Airports
Rome Ciampino Airport (CIA)29 min  ·  18.9 km
Roma-Fiumicino Airport (FCO)44 min  ·  29.1 km
Train
Roma San Pietro Train Station18 min  ·  1.5 km
Underground
Ottaviano metro5 min  ·  400 m
Get access to exclusive early booking discounts for your family’s upcoming getaway
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Property information and rules
Check-in
from 12:00-21:00
Check-out
until 10 am
Guest Parking
No parking available.
Internet
is available in for free.
Pets
Pets are not allowed.
Number of rooms:
6
FAQs
About Domus Serafino
What is the distance from Domus Serafino to the Vatican Museums?
Domus Serafino is located 600 meters from the Vatican Museums.
How far is Domus Serafino from Roma Termini railway station?
The hotel is 3 km from Roma Termini railway station.
What time is check-in and check-out at Domus Serafino?
Check-in at Domus Serafino is at 12:00 and check-out is until 10:00.
What are the nearest public transport options to Domus Serafino?
Ottaviano - San Pietro - Musei Vaticani metro station is 0.5 km away from the hotel.
Are there any dining options available near Domus Serafino?
Nearby dining options include Zi Gaetana, Il Matriciano, and Alla Rampa dei Gracchi, all within 300 meters.
What amenities are included in the rooms at Domus Serafino?
Rooms are equipped with air conditioning, a flat-screen TV, a tea/coffee maker, and free toiletries.
Is there Wi-Fi available at Domus Serafino?
Free Wi-Fi is available throughout the property.
Does Domus Serafino provide access for children?
Children under 12 years stay free at Domus Serafino.
Is smoking allowed at Domus Serafino?
Domus Serafino is a non-smoking hotel.
What is the nearest airport to Domus Serafino?
The nearest airport is Rome Ciampino Airport, located 16 km from the hotel.
Does Domus Serafino have a shared kitchen for guests?
Yes, there is a shared kitchen available at the property for guests.

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